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Men's Health

Testosterone: What the Evidence Actually Says

Symptoms attributed to low testosterone overlap heavily with sleep apnoea, depression and thyroid disease, and the market for treatment substantially exceeds the need.

Dr Amara Nwosu, PhD, RD Editor-in-chief and registered dietitian 3 min read 2 views
Testosterone: What the Evidence Actually Says

Key takeaways

  • Testing: a morning blood sample, repeated to confirm
  • Common alternative explanations: sleep apnoea, depression, thyroid disease, anaemia
  • Most useful single change: Ask for the other causes to be excluded before attributing symptoms to testosterone.
  • Commonest mistake: Buying testosterone or anabolic steroids online.
  • See a doctor if any of the signs under "When to speak to a doctor" below apply to you.

What it is

The main male sex hormone, and what genuinely raises or lowers it. It sits within Mens Health. The figures below are the ones published guidance uses, rather than the ones that circulate.

The numbers, in one place

Published figures for Testosterone
MeasureFigure
Testinga morning blood sample, repeated to confirm
Common alternative explanationssleep apnoea, depression, thyroid disease, anaemia
Associated with lower levelsobesity, poor sleep, heavy alcohol, some medicines
Effect of supplementation on fertilitysuppresses sperm production, sometimes profoundly
Anabolic steroidssuppress the body's own production

What helps

Here is what the evidence supports doing. Some of it will already be familiar.

  • Ask for the other causes to be excluded before attributing symptoms to testosterone
  • Address sleep, weight and alcohol, all of which affect levels
  • Have testing done in the morning and repeated before acting on it
  • Tell your GP about any steroid or testosterone use, including past use

What to avoid

The usual wrong turns. Some are more tempting than others.

  • Buying testosterone or anabolic steroids online
  • Taking testosterone while trying to conceive
  • Accepting treatment on the basis of a single test

Where to go next

When to speak to a doctor

See a GP rather than self-treating for persistent fatigue, low libido, low mood or erectile dysfunction — these have many causes, several of which are more common and more treatable than low testosterone. Seek urgent help for chest pain, severe mood change, or signs of a blood clot if you are on testosterone therapy.

Where this comes from

  • NICE — Hypogonadism clinical knowledge summary
  • NHS — Male menopause

How this page was put together

Every figure, recommendation and warning above is taken from the guidance named in Where this comes from. Nothing on this page is inferred, summarised or generalised beyond what those bodies publish: where they give a number, it is their number, and where they are silent, so are we. Pages are rebuilt whenever the underlying record changes. Sign-off by a named clinician, where it has happened, is shown at the top of the page along with the date.

Medical disclaimer

This article is general information, not medical advice. It cannot account for your own history, medication or circumstances. Always speak to a GP, pharmacist or another qualified health professional before making changes that affect your treatment, and never delay seeking medical advice because of something you have read here. In an emergency, call 999.

Spotted something wrong? Report an error on this page. We correct on the page and say what changed.

Dr Amara Nwosu

Editor-in-chief and a registered dietitian of fourteen years. Spent six of them in NHS outpatient clinics, which is where she learned that the advice people actually follow beats the advice that is technically optimal.

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